Next-Generation Sequencing Data Management
September 27-29, 2010 • Providence, RI
Matthias Zytnicki, Hadi Quesneville
Summary:
Several tools are now available for mapping high-throughput sequencing data from a genome, but few can extract biological knowledge from the mapped reads. We have developed a toolbox, S-MART, which handles mapped RNA-Seq and ChIP-Seq data. S-MART is an intuitive and lightweight tool, performing several tasks that are usually required during the analysis of mapped RNA-Seq and ChIP-Seq reads. For instance, S-MART provide a whole set of programs to analyze results of differential expressions experiments, including normalization and false rate discovery.
S-MART does not require a computer science background and thus can be used by all biologists through a graphical interface. S-MART can run on any personal computer, yielding results within an hour for most queries.
Availability and Implementation:
Source code is freely available for
download
. S-MART is supported on Linux, Mac and MS Windows.