GO Term : GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO

Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.
GO:0016725 oxidoreductase activity, acting on CH or CH2 groups Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

0 Protein

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0016728 GO:0004748
is_a GO:0003824 GO:0004748
is_a GO:0016491 GO:0004748
is_a GO:0016725 GO:0004748
is_a GO:0003674 GO:0004748
is_a GO:0004748 GO:0051061
is_a GO:0004748 GO:0051062
is_a GO:0004748 GO:0051063

20 Synonyms

Name Type
2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity synonym
2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity synonym
adenosylcobalamin-dependent ribonucleotide reductase activity synonym
aerobic non-heme iron-dependent ribonucleotide reductase activity synonym
anaerobic iron-sulfur-dependent ribonucleotide reductase activity synonym
class I ribonucleotide reductase activity synonym
class II ribonucleoside-diphosphate reductase activity synonym
class II ribonucleotide reductase activity synonym
nucleoside diphosphate reductase activity synonym
class III ribonucleotide reductase activity synonym
ribonucleoside 5'-diphosphate reductase activity synonym
purine/pyrimidine nucleoside diphosphate reduction synonym
ribonucleoside-diphosphate reductase activity synonym
ribonucleoside diphosphate reductase activity synonym
RNR synonym
ribonucleotide diphosphate reductase activity synonym
GO:0016960 alt_id
GO:0016959 alt_id
GO:0016961 alt_id
ribonucleotide reductase activity synonym