| Analysis | rpsblast_cdd | Start | 98 |
| End | 268 | Strand | + |
| Length | 171 | Note | Gaps:26 |
| Hit Coverage | 100.00 | Hit Length | 145 |
| Hit Pident | 53.10 | E Val | 6e-48 |
| Hit Description | cd03672 Dcp2p mRNA decapping enzyme 2 (Dcp2p) the catalytic subunit and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical N-terminal domain and a C-terminal domain which has the Nudix fold. While decapping is not dependent on the N-terminus of Dcp2p it does affect its efficiency. Dcp1p binds the N-terminal domain of Dcp2p stimulating the decapping activity of Dcp2p. Decapping permits the degradation of the transcript and is a site of numerous control inputs. It is responsible for nonsense-mediated decay as well as AU-rich element (ARE)-mediated decay. In addition it may also play a role in the levels of mRNA. Enzymes belonging to the Nudix superfamily require a divalent cation such as Mg2+ or Mn2+ for their activity and are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU where U I L or V).. | Hit Pcons | 17.24 |
| Name | Qrob_P0438930.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0438930.2 | Quercus robur | 95.0 | egn | (M=1) 3.6.1.62 - 5'-(N(7)-methylguanosine 5'-triphospho)-(mRNA) hydrolase. | EC:3.6.1.62 | validated |
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