GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P123050.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	aor:AO090011000685	27	510	484	n/a	80.00	495	51.52	17.42	1e-117	cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies
	ang:An08g03780	37	510	474	n/a	76.86	497	51.05	18.59	1e-111	hypothetical protein
	nfi:NFIA_106070	29	516	488	n/a	87.00	500	47.13	19.08	1e-110	toxin biosynthesis cytochrome P450 monooxygenase putative
	afm:AFUA_4G09980	29	515	487	n/a	80.52	534	47.44	19.07	1e-109	cytochrome P450 monooxygenase (EC:1.14.-.-) K00517
	aor:AO090001000028	28	510	483	n/a	85.51	490	44.87	21.48	1e-107	cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies
	ang:An09g01950	12	504	493	n/a	77.82	541	42.04	19.71	1e-106	hypothetical protein
	nfi:NFIA_089120	31	513	483	n/a	80.70	487	51.65	18.32	1e-105	benzoate 4-monooxygenase cytochrome P450
	fgr:FG08023.1	28	515	488	n/a	76.13	486	47.57	17.84	1e-103	hypothetical protein
	ssl:SS1G_13923	27	513	487	n/a	76.83	518	47.74	20.10	1e-100	hypothetical protein
	mgr:MGG_06544	29	513	485	n/a	76.28	506	50.26	18.91	1e-100	hypothetical protein
blastp_uniprot_sprot	sp\|O13317\|TRI11_FUSSP	28	511	484	n/a	81.91	492	42.43	19.85	2e-93	Isotrichodermin C-15 hydroxylase OS Fusarium sporotrichioides GN TRI11 PE 3 SV 1
	sp\|Q12609\|STCF_EMENI	28	501	474	n/a	86.40	478	42.37	19.13	2e-91	Probable sterigmatocystin biosynthesis P450 monooxygenase stcF OS Emericella nidulans GN stcF PE 3 SV 2
	sp\|Q12732\|AVNA_ASPPA	35	508	474	n/a	80.20	495	44.84	19.14	6e-91	Averantin oxidoreductase OS Aspergillus parasiticus GN avnA PE 1 SV 2
	sp\|Q00707\|STCL_EMENI	27	510	484	n/a	79.23	496	42.24	20.61	7e-85	Probable sterigmatocystin biosynthesis P450 monooxygenase stcL OS Emericella nidulans GN stcL PE 3 SV 2
	sp\|O00061\|CP67_UROFA	2	482	481	n/a	57.30	541	34.52	22.90	3e-38	Cytochrome P450 67 (Fragment) OS Uromyces fabae GN CYP67 PE 2 SV 1
	sp\|Q12608\|STCB_EMENI	35	474	440	n/a	48.74	517	34.92	19.05	1e-30	Probable sterigmatocystin biosynthesis P450 monooxygenase STCB OS Emericella nidulans GN stcB PE 3 SV 2
	sp\|P11707\|CP3A6_RABIT	139	512	374	n/a	51.10	501	32.42	23.44	1e-27	Cytochrome P450 3A6 OS Oryctolagus cuniculus GN CYP3A6 PE 2 SV 2
	sp\|Q12645\|PID9_FUSSO	30	491	462	n/a	56.12	515	31.83	21.11	2e-27	Pisatin demethylase OS Fusarium solani subsp. pisi GN PDAT9 PE 3 SV 1
	sp\|P24462\|CP3A7_HUMAN	133	483	351	n/a	47.12	503	32.91	22.36	7e-27	Cytochrome P450 3A7 OS Homo sapiens GN CYP3A7 PE 1 SV 2
	sp\|Q9JMA7\|CP341_MOUSE	133	487	355	n/a	49.60	504	31.60	24.00	9e-27	Cytochrome P450 3A41 OS Mus musculus GN Cyp3a41a PE 2 SV 1
blastp_pdb	2v0m_D	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	2v0m_C	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	2v0m_B	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	2v0m_A	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	2j0d_B	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	2j0d_A	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	1w0g_A	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	1w0f_A	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	1w0e_A	132	483	352	n/a	49.07	485	31.51	22.69	1e-24	mol:protein length:485 CYTOCHROME P450 3A4
	1tqn_A	132	483	352	n/a	48.97	486	31.51	22.69	1e-24	mol:protein length:486 cytochrome P450 3A4
rpsblast_cdd	gnl\|CDD\|109135	134	492	359	Gaps:19	77.56	459	29.49	18.26	3e-53	pfam00067 p450 Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander' a four-helix bundle helices J and K and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron) the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.
	gnl\|CDD\|32307	133	491	359	Gaps:57	73.48	411	33.77	15.23	4e-37	COG2124 CypX Cytochrome P450 [Secondary metabolites biosynthesis transport and catabolism].
	gnl\|CDD\|133882	60	100	41	Gaps:3	6.69	568	31.58	26.32	1.8	PHA00430 PHA00430 tail fiber protein.
	gnl\|CDD\|117924	172	253	82	Gaps:20	78.10	105	24.39	12.20	3.9	pfam09382 RQC RQC domain. This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain found only in RecQ family enzymes is a high affinity G4 DNA binding domain.
	gnl\|CDD\|137552	430	455	26	Gaps:1	3.85	702	29.63	29.63	3.9	PRK09849 PRK09849 putative oxidoreductase Provisional.
rpsblast_kog	gnl\|CDD\|35380	125	510	386	Gaps:31	77.56	499	28.94	18.35	9e-52	KOG0158 KOG0158 KOG0158 Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies [Secondary metabolites biosynthesis transport and catabolism].
	gnl\|CDD\|35379	16	488	473	Gaps:38	93.96	497	24.41	17.34	5e-47	KOG0157 KOG0157 KOG0157 Cytochrome P450 CYP4/CYP19/CYP26 subfamilies [Secondary metabolites biosynthesis transport and catabolism Lipid transport and metabolism].
	gnl\|CDD\|35378	23	490	468	Gaps:24	95.30	489	25.54	17.38	2e-42	KOG0156 KOG0156 KOG0156 Cytochrome P450 CYP2 subfamily [Secondary metabolites biosynthesis transport and catabolism].
	gnl\|CDD\|35381	43	489	447	Gaps:55	86.32	519	25.45	16.74	2e-33	KOG0159 KOG0159 KOG0159 Cytochrome P450 CYP11/CYP12/CYP24/CYP27 subfamilies [Secondary metabolites biosynthesis transport and catabolism].
	gnl\|CDD\|35903	146	486	341	Gaps:37	69.14	486	23.21	19.35	2e-16	KOG0684 KOG0684 KOG0684 Cytochrome P450 [Secondary metabolites biosynthesis transport and catabolism].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	A1CLP1	290817	292471	517	46.64	92.07	n/a	Benzoate 4-monooxygenase cytochrome P450 - Aspergillus clavatus
	A1CHU3	290817	292471	519	47.71	92.49	n/a	Toxin biosynthesis cytochrome P450 monooxygenase putative - Aspergillus clavatus
	A1CWW7	290817	292465	500	47.27	95.20	n/a	Toxin biosynthesis cytochrome P450 monooxygenase putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q4WPP4	290975	292465	534	45.43	84.08	n/a	Cytochrome P450 monooxygenase putative - Aspergillus fumigatus (Sartorya fumigata)
	Q2UPC4	290817	292468	490	42.09	95.51	n/a	Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies - Aspergillus oryzae
	A1CGF7	290817	292459	487	44.03	94.66	n/a	Toxin biosynthesis cytochrome P450 monooxygenase putative - Aspergillus clavatus
	A1C7G2	290921	292474	510	43.83	89.02	n/a	Benzoate 4-monooxygenase cytochrome P450 - Aspergillus clavatus
	A4R473	290817	292423	533	41.41	85.18	n/a	Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea)
	A7F8M6	290808	292471	531	39.84	94.54	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A2QH38	290805	292468	518	40.56	89.96	n/a	Contig An03c0180 complete genome. - Aspergillus niger
blastx_FNG31_prot	gi:70993962:ref:XP_751828.1:	290975	292465	534	45.43	84.08	n/a	Aspergillus fumigatus Af293 cytochrome P450 monooxygenase
	FG08023.1	290802	292468	486	45.13	93.00	n/a	fusarium_graminearum hypothetical protein 487 aa
	AO090001000028	290817	292468	490	42.09	95.51	n/a	Aspergillus oryzae cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies
	jgi:Triree:39657	290823	292468	490	41.09	93.88	n/a	Trichoderma reesei
	MGG_03832.5	290817	292423	533	41.41	85.18	n/a	magnaporthe_grisea hypothetical protein translation 534 aa
	jgi:Triree:36464	290823	292080	432	46.61	85.42	n/a	Trichoderma reesei
	SS1G_13957.1	290808	292471	531	39.84	94.54	n/a	sclerotinia_sclerotiorum hypothetical protein translation 532 aa
	SNU00902.1	290808	292092	500	43.42	76.00	n/a	Stagonospora nodorum hypothetical protein translation
	AO090005000553	291029	292468	494	40.29	83.40	n/a	Aspergillus oryzae cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies
	jgi:Triree:40740	290838	292474	482	39.69	94.61	n/a	Trichoderma reesei
blat_BES	no results
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_08051.2:gb:EAT84327	290990	292468	512	39.39	83.79	n/a	n/a
	gnl:WGS:AAGI:SNOT_14681.2:gb:EAT77873	290918	292468	501	36.50	92.42	n/a	n/a
	gnl:WGS:AAGI:SNOT_00902.2:gb:EAT92397	291026	292077	368	43.01	77.72	n/a	n/a
	gnl:WGS:AAGI:SNOT_07865.2:gb:EAT85331	290823	292053	513	36.36	70.76	n/a	n/a
	gnl:WGS:AAGI:SNOT_05492.2:gb:EAT86556	290808	292107	471	37.23	79.83	n/a	n/a
	gnl:WGS:AAGI:SNOT_10480.2:gb:EAT81874	290820	291634	262	40.16	96.95	n/a	n/a
	gnl:WGS:AAGI:SNOT_08270.2:gb:EAT84546	290921	291808	308	35.93	95.78	n/a	n/a
	gnl:WGS:AAGI:SNOT_07598.2:gb:EAT85064	290918	291772	484	36.15	61.16	n/a	n/a
	gnl:WGS:AAGI:SNOT_07018.1:gb:EAT85669	290802	291490	210	41.83	99.05	n/a	n/a
	gnl:WGS:AAGI:SNOT_02565.1:gb:EAT89296	291014	292074	379	34.14	87.34	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	no results
sim4_lm_allest6_clctg	no results
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q12732	290823	292104	495	42.63	76.77	n/a	Averantin oxidoreductase - Aspergillus parasiticus
	O13317	290814	292080	492	41.44	76.02	n/a	Isotrichodermin C-15 hydroxylase - Fusarium sporotrichioides
	Q12609	290844	292104	478	40.27	77.41	n/a	Probable sterigmatocystin biosynthesis P450 monooxygenase stcF - Emericella nidulans (Aspergillus nidulans)
	Q00707	290817	292483	500	39.19	94.40	n/a	Probable sterigmatocystin biosynthesis P450 monooxygenase stcL - Emericella nidulans (Aspergillus nidulans)
	O00061	290901	291622	541	31.98	41.04	n/a	Cytochrome P450 67 - Uromyces fabae (Rust fungus)
	Q9JMA7	291026	292080	504	28.30	63.10	n/a	Cytochrome P450 3A41 - Mus musculus (Mouse)
REPET	no results
MUMer_show_coords_lm_WA74	no results