GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P109370.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ssl:SS1G_11436	1	234	234	n/a	98.73	237	62.39	14.53	3e-95	hypothetical protein
	bfu:BC1G_08885	1	234	234	n/a	98.73	237	61.97	15.81	5e-95	hypothetical protein
	afm:AFUA_5G13470	1	227	227	n/a	91.50	247	58.85	19.47	1e-79	60S acidic ribosomal protein P0
	nfi:NFIA_073590	1	227	227	n/a	91.50	247	58.85	19.47	3e-79	60S acidic ribosomal protein P0 putative
	ncr:NCU07547	1	230	230	n/a	90.08	252	54.19	22.03	5e-78	similar to 60S acidic ribosomal protein
	fgr:FG06705.1	1	230	230	n/a	93.03	244	54.19	20.26	3e-76	hypothetical protein
	aor:AO090120000495	1	227	227	n/a	91.50	247	57.52	18.58	3e-76	protein involved in mRNA turnover
	ani:AN6902.2	1	227	227	n/a	91.87	246	56.19	20.80	1e-75	hypothetical protein
	spo:SPBC11G11.03	1	227	227	n/a	94.19	241	52.42	18.50	4e-75	60S acidic ribosomal protein (predicted)
	yli:YALI0F31317g	1	227	227	n/a	97.42	233	48.46	21.59	1e-69	YALI0F31317p
blastp_uniprot_sprot	sp\|Q7S302\|MRT4_NEUCR	1	230	230	n/a	90.08	252	54.19	22.03	5e-79	mRNA turnover protein 4 homolog OS Neurospora crassa GN NCU07547 PE 3 SV 1
	sp\|Q9USZ6\|MRT4_SCHPO	1	227	227	n/a	94.19	241	52.42	18.50	5e-76	mRNA turnover protein 4 homolog OS Schizosaccharomyces pombe GN SPBC11G11.03 PE 2 SV 1
	sp\|Q6FJ04\|MRT4_CANGA	1	230	230	n/a	96.65	239	47.19	22.94	1e-66	mRNA turnover protein 4 homolog OS Candida glabrata GN MRT4 PE 3 SV 1
	sp\|P33201\|MRT4_YEAST	1	227	227	n/a	96.61	236	42.98	26.32	4e-60	mRNA turnover protein 4 OS Saccharomyces cerevisiae GN MRT4 PE 1 SV 1
	sp\|Q9D0I8\|MRT4_MOUSE	1	217	217	n/a	83.68	239	49.50	19.00	4e-55	mRNA turnover protein 4 homolog OS Mus musculus GN Mrto4 PE 2 SV 1
	sp\|A4FV84\|MRT4_BOVIN	1	231	231	n/a	89.54	239	46.26	19.63	6e-55	mRNA turnover protein 4 homolog OS Bos taurus GN MRTO4 PE 2 SV 1
	sp\|Q9UKD2\|MRT4_HUMAN	1	231	231	n/a	89.54	239	45.79	20.56	2e-54	mRNA turnover protein 4 homolog OS Homo sapiens GN MRTO4 PE 1 SV 2
	sp\|Q75DK9\|MRT4_ASHGO	1	230	230	n/a	97.88	236	45.02	20.78	3e-42	mRNA turnover protein 4 homolog OS Ashbya gossypii GN MRT4 PE 3 SV 1
	sp\|Q86HD3\|MRT4_DICDI	1	235	235	n/a	100.00	223	41.70	20.18	8e-35	mRNA turnover protein 4 homolog OS Dictyostelium discoideum GN mrt4 PE 3 SV 1
blastp_pdb	no results
rpsblast_cdd	gnl\|CDD\|88596	21	195	175	Gaps:12	100.00	163	58.90	16.56	8e-64	cd05796 Ribosomal_P0_like Ribosomal protein L10 family P0-like protein subfamily composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0 including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be involved in mRNA decay. P0 forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. It occupies the L7/L12 stalk of the ribosome. The stalk is known to contain the binding site for elongation factors EF-G and EF-Tu however there is disagreement as to whether or not P0 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line P0 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). Some eukaryotic P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2..
	gnl\|CDD\|88594	25	191	167	Gaps:28	97.42	155	27.81	14.57	4e-19	cd00379 Ribosomal_L10_P0 Ribosomal protein L10 family composed of the large subunit ribosomal protein called L10 in bacteria P0 in eukaryotes and L10e in archaea as well as uncharacterized P0-like eukaryotic proteins. In all three kingdoms L10 forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein and forms the base of the L7/L12 stalk while the extended C-terminal helix binds to two or three dimers of the NTD of L7/L12 (L7 and L12 are identical except for an acetylated N-terminus). The L7/L12 stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu respectively) however there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). Some eukaryotic P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2..
	gnl\|CDD\|88595	25	207	183	Gaps:16	96.57	175	24.85	21.89	1e-17	cd05795 Ribosomal_P0_L10e Ribosomal protein L10 family P0 and L10e subfamily composed of eukaryotic 60S ribosomal protein P0 and the archaeal P0 homolog L10e. P0 or L10e forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk structure on the large subunit of the ribosome. The stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu respectively) however there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). These eukaryotic and archaeal P0 sequences have an additional C-terminal domain homologous with acidic proteins P1 and P2..
	gnl\|CDD\|135013	25	220	196	Gaps:17	55.18	328	27.07	22.10	5e-13	PRK04019 rplP0 acidic ribosomal protein P0 Validated.
	gnl\|CDD\|30593	25	193	169	Gaps:16	94.29	175	14.55	19.39	6e-08	COG0244 RplJ Ribosomal protein L10 [Translation ribosomal structure and biogenesis].
rpsblast_kog	gnl\|CDD\|36034	1	234	234	Gaps:13	100.00	223	49.33	19.73	5e-65	KOG0816 KOG0816 KOG0816 Protein involved in mRNA turnover [RNA processing and modification].
	gnl\|CDD\|36033	27	220	194	Gaps:16	73.47	245	25.56	21.67	5e-10	KOG0815 KOG0815 KOG0815 60S acidic ribosomal protein P0 [Translation ribosomal structure and biogenesis].
	gnl\|CDD\|36282	144	224	81	n/a	3.32	2439	20.99	18.52	0.14	KOG1064 KOG1064 KOG1064 RAVE (regulator of V-ATPase assembly) complex subunit RAV1/DMX protein WD repeat superfamily [General function prediction only].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0TWV1	936588	937342	268	86.38	87.69	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A7F1G6	936588	937339	237	62.39	98.73	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	Q4WVV7	936588	937318	247	56.65	94.33	n/a	60S acidic ribosomal protein P0 putative - Aspergillus fumigatus (Sartorya fumigata)
	A1DDI6	936588	937318	247	56.65	94.33	n/a	60S acidic ribosomal protein P0 putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	A1CBT1	936588	937318	248	55.79	93.95	n/a	60S acidic ribosomal protein P0 putative - Aspergillus clavatus
	Q1DK04	936588	937318	244	55.22	94.26	n/a	Putative uncharacterized protein - Coccidioides immitis
	Q2U5V6	936588	937339	247	54.92	98.79	n/a	Protein involved in mRNA turnover - Aspergillus oryzae
	Q5AXS8	936588	937318	246	54.51	94.72	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	A2R3N7	936588	937318	234	54.75	94.44	n/a	Phenotype: S. cerevisiae MRT4 null mutants are viable - Aspergillus niger
	Q6CVA4	936588	937327	238	44.59	97.06	n/a	Similar to sp:P33201 Saccharomyces cerevisiae YKL009w MRT4 mRNA turnover 4 singleton - Kluyveromyces lactis (Yeast) (Candida sphaerica)
	Q0TWV1	936588	937342	268	86.38	87.69	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A7F1G6	936588	937339	237	62.39	98.73	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	Q4WVV7	936588	937318	247	56.65	94.33	n/a	60S acidic ribosomal protein P0 putative - Aspergillus fumigatus (Sartorya fumigata)
	A1DDI6	936588	937318	247	56.65	94.33	n/a	60S acidic ribosomal protein P0 putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	A1CBT1	936588	937318	248	55.79	93.95	n/a	60S acidic ribosomal protein P0 putative - Aspergillus clavatus
	Q1DK04	936588	937318	244	55.22	94.26	n/a	Putative uncharacterized protein - Coccidioides immitis
	Q2U5V6	936588	937339	247	54.92	98.79	n/a	Protein involved in mRNA turnover - Aspergillus oryzae
	Q5AXS8	936588	937318	246	54.51	94.72	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	A2R3N7	936588	937318	234	54.75	94.44	n/a	Phenotype: S. cerevisiae MRT4 null mutants are viable - Aspergillus niger
	Q6CVA4	936588	937327	238	44.59	97.06	n/a	Similar to sp:P33201 Saccharomyces cerevisiae YKL009w MRT4 mRNA turnover 4 singleton - Kluyveromyces lactis (Yeast) (Candida sphaerica)
blastx_FNG31_prot	SNU16023.1	936588	937342	235	86.38	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	SS1G_11436.1	936588	937339	237	62.39	98.73	n/a	sclerotinia_sclerotiorum hypothetical protein translation 238 aa
	gi:70997105:ref:XP_753307.1:	936588	937318	247	56.65	94.33	n/a	Aspergillus fumigatus Af293 60S acidic ribosomal protein
	CIMG_09359.2	936588	937318	244	55.22	94.26	n/a	Coccidioides immitis hypothetical protein translation 245 aa
	AO090120000495	936588	937339	247	54.92	98.79	n/a	Aspergillus oryzae protein involved in mRNA turnover
	AN6902	936588	937318	246	54.51	94.72	n/a	Aspergillus nidulans AN6902.3 conserved hypothetical protein translation 247 aa
	NCU07547.2	936588	937327	252	52.12	93.65	n/a	Neurospora crassa hypothetical protein translation 253 aa
	FG06705.1	936588	937342	244	51.85	99.59	n/a	fusarium_graminearum hypothetical protein 245 aa
	jgi:Triree:35949	936588	937327	248	50.42	95.16	n/a	Trichoderma reesei
	gi:50294758:ref:XP_449790.1:	936588	937327	239	47.19	96.65	n/a	Candida glabrata CBS138 hypothetical protein CAGL0M10197g
	SNU16023.1	936588	937342	235	86.38	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	SS1G_11436.1	936588	937339	237	62.39	98.73	n/a	sclerotinia_sclerotiorum hypothetical protein translation 238 aa
	gi:70997105:ref:XP_753307.1:	936588	937318	247	56.65	94.33	n/a	Aspergillus fumigatus Af293 60S acidic ribosomal protein
	CIMG_09359.2	936588	937318	244	55.22	94.26	n/a	Coccidioides immitis hypothetical protein translation 245 aa
	AO090120000495	936588	937339	247	54.92	98.79	n/a	Aspergillus oryzae protein involved in mRNA turnover
	AN6902	936588	937318	246	54.51	94.72	n/a	Aspergillus nidulans AN6902.3 conserved hypothetical protein translation 247 aa
	NCU07547.2	936588	937327	252	52.12	93.65	n/a	Neurospora crassa hypothetical protein translation 253 aa
	FG06705.1	936588	937342	244	51.85	99.59	n/a	fusarium_graminearum hypothetical protein 245 aa
	jgi:Triree:35949	936588	937327	248	50.42	95.16	n/a	Trichoderma reesei
	gi:50294758:ref:XP_449790.1:	936588	937327	239	47.19	96.65	n/a	Candida glabrata CBS138 hypothetical protein CAGL0M10197g
blat_BES	QS0AAD29ZD03FM1	936321	936772	839	n/a	n/a	n/a	n/a
blat_BES	QS0AAD5ZF05RM1	936321	937025	770	n/a	n/a	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_16023.2:gb:EAT76602	936588	937342	268	86.38	87.69	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_16023.2:gb:EAT76602	936588	937342	268	86.38	87.69	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	RS0AAC6YE21FM1	936712	937338	577	99.65	100.00	n/a	Lm isolate M1 - V8 (5 days) and minimal medium (8 hours) mycelial library
	RS0AAC6YD13FM1	936712	937341	580	99.48	100.00	n/a	Lm isolate M1 - V8 (5 days) and minimal medium (8 hours) mycelial library
	RS0AAB9YP03FM1	936927	937460	535	98.69	100.00	n/a	Lm isolate M1 - mycelia grown for 5 days and 8 hours on oilseed rape juice medium
	RS0AAC13YE01FM1	936712	937353	592	99.49	100.00	n/a	Lm isolate M1 - V8 (5 days) and minimal medium (8 hours) mycelial library
sim4_lm_allest6_clctg	CL_lm_SuperContig_18_v2_lmctg_1480_v2_008.Contig1_v6	936712	937460	700	99.14	100.00	n/a	n/a
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q7S302	936588	937327	252	52.12	93.65	n/a	mRNA turnover protein 4 homolog - Neurospora crassa
	Q6FJ04	936588	937327	239	47.19	96.65	n/a	mRNA turnover protein 4 homolog - Candida glabrata (Yeast) (Torulopsis glabrata)
	P33201	936588	937318	236	42.98	96.61	n/a	mRNA turnover protein 4 - Saccharomyces cerevisiae (Baker's yeast)
	Q75DK9	936588	937327	236	44.59	97.88	n/a	mRNA turnover protein 4 homolog - Ashbya gossypii (Yeast) (Eremothecium gossypii)
	Q9USZ6	936827	937318	241	54.88	68.05	n/a	mRNA turnover protein 4 homolog - Schizosaccharomyces pombe (Fission yeast)
	Q9D0I8	936588	937288	239	48.29	85.77	n/a	mRNA turnover protein 4 homolog - Mus musculus (Mouse)
	Q9UKD2	936588	937330	239	44.75	91.63	n/a	mRNA turnover protein 4 homolog - Homo sapiens (Human)
	Q7S302	936588	937327	252	52.12	93.65	n/a	mRNA turnover protein 4 homolog - Neurospora crassa
	Q6FJ04	936588	937327	239	47.19	96.65	n/a	mRNA turnover protein 4 homolog - Candida glabrata (Yeast) (Torulopsis glabrata)
	P33201	936588	937318	236	42.98	96.61	n/a	mRNA turnover protein 4 - Saccharomyces cerevisiae (Baker's yeast)
	Q75DK9	936588	937327	236	44.59	97.88	n/a	mRNA turnover protein 4 homolog - Ashbya gossypii (Yeast) (Eremothecium gossypii)
	Q9D0I8	936588	937288	239	48.29	85.77	n/a	mRNA turnover protein 4 homolog - Mus musculus (Mouse)
	Q9UKD2	936588	937330	239	44.75	91.63	n/a	mRNA turnover protein 4 homolog - Homo sapiens (Human)
REPET	no results
MUMer_show_coords_lm_WA74	no results