Study : Rationally-designed APOBEC3B cytosine base editors with improved specificity

Identification

• Name: Rationally-designed APOBEC3B cytosine base editors with improved specificity
• Identifier: dXJuOkVWQS9zdHVkeS9QUkpOQTYwMjYwOA==
• Data link: Link to this study on EBI European Nucleotide Archive
• Description: Increasing the specificity of base editing with engineered Cas9-APOBEC3B deaminase fusions, the related data including rice reference sequence, rice plants whole-genome sequences and targets replicon deep sequences.
• Data files: SRR11144543; SRR11144780; SRR11144895; SRR11144894; SRR11144883; SRR11144872; SRR11144840; SRR11144829; SRR11144818; SRR11144856; SRR11144845; SRR11144843; SRR11144893; SRR11144892; SRR11144891; SRR11144890; SRR11144889; SRR11144888; SRR11144887; SRR11144886

Genotype

Accession number	Name	Taxon
	A3A-BE3	Oryza sativa Japonica Group A3A-BE3-#1 / A3A-BE3-#2 / A3A-BE3-#3 / A3A-BE3-#4 / A3A-BE3-#5 / A3A-BE3-#6 / A3A-BE3-#7 / A3A-BE3-#8 / A3A-BE3-#9 / Zhonghua 11
	OsCDC48_SaT1	Oryza sativa Japonica Group OsCDC48_SaT1_A3A_Rep1 / OsCDC48_SaT1_A3A_Rep2 / OsCDC48_SaT1_A3A_Rep3 / OsCDC48_SaT1_A3A_Rep4 / OsCDC48_SaT1_A3B_Rep1 / OsCDC48_SaT1_A3B_Rep2 / OsCDC48_SaT1_A3B_Rep3 / OsCDC48_SaT1_A3B_Rep4 / OsCDC48_SaT1_A3Bctd_Rep1 / OsCDC48_SaT1_A3Bctd_Rep2 / OsCDC48_SaT1_A3Bctd_Rep3 / OsCDC48_SaT1_A3Bctd_Rep4 / OsCDC48_SaT1_BE3_Rep1 / OsCDC48_SaT1_BE3_Rep2 / OsCDC48_SaT1_BE3_Rep3 / OsCDC48_SaT1_BE3_Rep4 / OsCDC48_SaT1_CK_Rep1 / OsCDC48_SaT1_CK_Rep2 / OsCDC48_SaT1_CK_Rep3 / OsCDC48_SaT1_CK_Rep4 / OsCDC48_SaT1_CK_Rep5 / OsCDC48_SaT1_D314H_Rep1 / OsCDC48_SaT1_D314H_Rep2 / OsCDC48_SaT1_D314H_Rep3 / OsCDC48_SaT1_D314H_Rep4 / OsCDC48_SaT1_D314R_Rep1 / OsCDC48_SaT1_D314R_Rep2 / OsCDC48_SaT1_D314R_Rep3 / OsCDC48_SaT1_D314R_Rep4 / OsCDC48_SaT1_F308K_Rep1 / OsCDC48_SaT1_F308K_Rep2 / OsCDC48_SaT1_F308K_Rep3 / OsCDC48_SaT1_F308K_Rep4 / OsCDC48_SaT1_KF1_Rep1 / OsCDC48_SaT1_KF1_Rep2 / OsCDC48_SaT1_KF1_Rep3 / OsCDC48_SaT1_KF1_Rep4 / OsCDC48_SaT1_KF2_Rep1 / OsCDC48_SaT1_KF2_Rep2 / OsCDC48_SaT1_KF2_Rep3 / OsCDC48_SaT1_KF2_Rep4 / OsCDC48_SaT1_KKR_Rep1 / OsCDC48_SaT1_KKR_Rep2 / OsCDC48_SaT1_KKR_Rep3 / OsCDC48_SaT1_KKR_Rep4 / OsCDC48_SaT1_KK_Rep1 / OsCDC48_SaT1_KK_Rep2 / OsCDC48_SaT1_KK_Rep3 / OsCDC48_SaT1_KK_Rep4 / OsCDC48_SaT1_KR_Rep1 / OsCDC48_SaT1_KR_Rep2 / OsCDC48_SaT1_KR_Rep3 / OsCDC48_SaT1_KR_Rep4 / OsCDC48_SaT1_KVF_Rep1 / OsCDC48_SaT1_KVF_Rep2 / OsCDC48_SaT1_KVF_Rep3 / OsCDC48_SaT1_KVF_Rep4 / OsCDC48_SaT1_L230K_Rep1 / OsCDC48_SaT1_L230K_Rep2 / OsCDC48_SaT1_L230K_Rep3 / OsCDC48_SaT1_L230K_Rep4 / OsCDC48_SaT1_N240A_Rep1 / OsCDC48_SaT1_N240A_Rep2 / OsCDC48_SaT1_N240A_Rep3 / OsCDC48_SaT1_N240A_Rep4 / OsCDC48_SaT1_R128A_Rep1 / OsCDC48_SaT1_R128A_Rep2 / OsCDC48_SaT1_R128A_Rep3 / OsCDC48_SaT1_R128A_Rep4 / OsCDC48_SaT1_R210A_Rep1 / OsCDC48_SaT1_R210A_Rep2 / OsCDC48_SaT1_R210A_Rep3 / OsCDC48_SaT1_R210A_Rep4 / OsCDC48_SaT1_R210K_Rep1 / OsCDC48_SaT1_R210K_Rep2 / OsCDC48_SaT1_R210K_Rep3 / OsCDC48_SaT1_R210K_Rep4 / OsCDC48_SaT1_R211K_Rep1 / OsCDC48_SaT1_R211K_Rep2 / OsCDC48_SaT1_R211K_Rep3 / OsCDC48_SaT1_R211K_Rep4 / OsCDC48_SaT1_R311K_Rep1 / OsCDC48_SaT1_R311K_Rep2 / OsCDC48_SaT1_R311K_Rep3 / OsCDC48_SaT1_R311K_Rep4 / OsCDC48_SaT1_RK_Rep1 / OsCDC48_SaT1_RK_Rep2 / OsCDC48_SaT1_RK_Rep3 / OsCDC48_SaT1_RK_Rep4 / OsCDC48_SaT1_RM_Rep1 / OsCDC48_SaT1_RM_Rep2 / OsCDC48_SaT1_RM_Rep3 / OsCDC48_SaT1_RM_Rep4 / OsCDC48_SaT1_T214C_Rep1 / OsCDC48_SaT1_T214C_Rep2 / OsCDC48_SaT1_T214C_Rep3 / OsCDC48_SaT1_T214C_Rep4 / OsCDC48_SaT1_T214G_Rep1 / OsCDC48_SaT1_T214G_Rep2 / OsCDC48_SaT1_T214G_Rep3 / OsCDC48_SaT1_T214G_Rep4 / OsCDC48_SaT1_T214S_Rep1 / OsCDC48_SaT1_T214S_Rep2 / OsCDC48_SaT1_T214S_Rep3 / OsCDC48_SaT1_T214S_Rep4 / OsCDC48_SaT1_T214V_Rep1 / OsCDC48_SaT1_T214V_Rep2 / OsCDC48_SaT1_T214V_Rep3 / OsCDC48_SaT1_T214V_Rep4 / OsCDC48_SaT1_VHM_Rep1 / OsCDC48_SaT1_VHM_Rep2 / OsCDC48_SaT1_VHM_Rep3 / OsCDC48_SaT1_VHM_Rep4 / OsCDC48_SaT1_VR_Rep1 / OsCDC48_SaT1_VR_Rep2 / OsCDC48_SaT1_VR_Rep3 / OsCDC48_SaT1_VR_Rep4 / OsCDC48_SaT1_W281H_Rep1 / OsCDC48_SaT1_W281H_Rep2 / OsCDC48_SaT1_W281H_Rep3 / OsCDC48_SaT1_W281H_Rep4 / OsCDC48_SaT1_Y130F_Rep1 / OsCDC48_SaT1_Y130F_Rep2 / OsCDC48_SaT1_Y130F_Rep3 / OsCDC48_SaT1_Y130F_Rep4 / OsCDC48_SaT1_Y313F_Rep1 / OsCDC48_SaT1_Y313F_Rep2 / OsCDC48_SaT1_Y313F_Rep3 / OsCDC48_SaT1_Y313F_Rep4 / OsCDC48_SaT1_Y315M_Rep1 / OsCDC48_SaT1_Y315M_Rep2 / OsCDC48_SaT1_Y315M_Rep3 / OsCDC48_SaT1_Y315M_Rep4 / OsCDC48_SaT1_YEE_Rep1 / OsCDC48_SaT1_YEE_Rep2 / OsCDC48_SaT1_YEE_Rep3 / OsCDC48_SaT1_YEE_Rep4 / OsCDC48_SaT1_dSaCas9_Rep1 / OsCDC48_SaT1_dSaCas9_Rep2 / OsCDC48_SaT1_dSaCas9_Rep3 / OsCDC48_SaT1_eA3A_Rep1 / OsCDC48_SaT1_eA3A_Rep2 / OsCDC48_SaT1_eA3A_Rep3 / OsCDC48_SaT1_eA3A_Rep4 / OsCDC48_SaT1_nSaCas9_Rep1 / OsCDC48_SaT1_nSaCas9_Rep2 / OsCDC48_SaT1_nSaCas9_Rep3 / OsCDC48_SaT1_ssDNA_CK_Rep1 / OsCDC48_SaT1_ssDNA_CK_Rep2 / OsCDC48_SaT1_ssDNA_CK_Rep3 / Zhonghua 11
	OsDEP1_SaT1	Oryza sativa Japonica Group OsDEP1_SaT1_A3A_Rep1 / OsDEP1_SaT1_A3A_Rep2 / OsDEP1_SaT1_A3A_Rep3 / OsDEP1_SaT1_A3B_Rep1 / OsDEP1_SaT1_A3B_Rep2 / OsDEP1_SaT1_A3B_Rep3 / OsDEP1_SaT1_A3Bctd_Rep1 / OsDEP1_SaT1_A3Bctd_Rep2 / OsDEP1_SaT1_A3Bctd_Rep3 / OsDEP1_SaT1_BE3_Rep1 / OsDEP1_SaT1_BE3_Rep2 / OsDEP1_SaT1_BE3_Rep3 / OsDEP1_SaT1_CK_Rep1 / OsDEP1_SaT1_CK_Rep2 / OsDEP1_SaT1_CK_Rep3 / OsDEP1_SaT1_CK_Rep4 / OsDEP1_SaT1_D314H_Rep1 / OsDEP1_SaT1_D314H_Rep2 / OsDEP1_SaT1_D314H_Rep3 / OsDEP1_SaT1_D314R_Rep1 / OsDEP1_SaT1_D314R_Rep2 / OsDEP1_SaT1_D314R_Rep3 / OsDEP1_SaT1_F308K_Rep1 / OsDEP1_SaT1_F308K_Rep2 / OsDEP1_SaT1_F308K_Rep3 / OsDEP1_SaT1_KF1_Rep1 / OsDEP1_SaT1_KF1_Rep2 / OsDEP1_SaT1_KF1_Rep3 / OsDEP1_SaT1_KF1_Rep4 / OsDEP1_SaT1_KF2_Rep1 / OsDEP1_SaT1_KF2_Rep2 / OsDEP1_SaT1_KF2_Rep3 / OsDEP1_SaT1_KKR_Rep1 / OsDEP1_SaT1_KKR_Rep2 / OsDEP1_SaT1_KKR_Rep3 / OsDEP1_SaT1_KKR_Rep4 / OsDEP1_SaT1_KK_Rep1 / OsDEP1_SaT1_KK_Rep2 / OsDEP1_SaT1_KK_Rep3 / OsDEP1_SaT1_KK_Rep4 / OsDEP1_SaT1_KR_Rep1 / OsDEP1_SaT1_KR_Rep2 / OsDEP1_SaT1_KR_Rep3 / OsDEP1_SaT1_KR_Rep4 / OsDEP1_SaT1_KVF_Rep1 / OsDEP1_SaT1_KVF_Rep2 / OsDEP1_SaT1_KVF_Rep3 / OsDEP1_SaT1_L230K_Rep1 / OsDEP1_SaT1_L230K_Rep2 / OsDEP1_SaT1_L230K_Rep3 / OsDEP1_SaT1_N240A_Rep1 / OsDEP1_SaT1_N240A_Rep2 / OsDEP1_SaT1_N240A_Rep3 / OsDEP1_SaT1_R128A_Rep1 / OsDEP1_SaT1_R128A_Rep2 / OsDEP1_SaT1_R128A_Rep3 / OsDEP1_SaT1_R210A_Rep1 / OsDEP1_SaT1_R210A_Rep2 / OsDEP1_SaT1_R210A_Rep3 / OsDEP1_SaT1_R210K_Rep1 / OsDEP1_SaT1_R210K_Rep2 / OsDEP1_SaT1_R210K_Rep3 / OsDEP1_SaT1_R211K_Rep1 / OsDEP1_SaT1_R211K_Rep2 / OsDEP1_SaT1_R211K_Rep3 / OsDEP1_SaT1_R311K_Rep1 / OsDEP1_SaT1_R311K_Rep2 / OsDEP1_SaT1_R311K_Rep3 / OsDEP1_SaT1_RK_Rep1 / OsDEP1_SaT1_RK_Rep2 / OsDEP1_SaT1_RK_Rep3 / OsDEP1_SaT1_RM_Rep1 / OsDEP1_SaT1_RM_Rep2 / OsDEP1_SaT1_RM_Rep3 / OsDEP1_SaT1_T214C_Rep1 / OsDEP1_SaT1_T214C_Rep2 / OsDEP1_SaT1_T214C_Rep3 / OsDEP1_SaT1_T214G_Rep1 / OsDEP1_SaT1_T214G_Rep2 / OsDEP1_SaT1_T214G_Rep3 / OsDEP1_SaT1_T214G_Rep4 / OsDEP1_SaT1_T214S_Rep1 / OsDEP1_SaT1_T214S_Rep2 / OsDEP1_SaT1_T214S_Rep3 / OsDEP1_SaT1_T214V_Rep1 / OsDEP1_SaT1_T214V_Rep2 / OsDEP1_SaT1_T214V_Rep3 / OsDEP1_SaT1_VHM_Rep1 / OsDEP1_SaT1_VHM_Rep2 / OsDEP1_SaT1_VHM_Rep3 / OsDEP1_SaT1_VR_Rep1 / OsDEP1_SaT1_VR_Rep2 / OsDEP1_SaT1_VR_Rep3 / OsDEP1_SaT1_VR_Rep4 / OsDEP1_SaT1_W281H_Rep1 / OsDEP1_SaT1_W281H_Rep2 / OsDEP1_SaT1_W281H_Rep3 / OsDEP1_SaT1_Y130F_Rep1 / OsDEP1_SaT1_Y130F_Rep2 / OsDEP1_SaT1_Y130F_Rep3 / OsDEP1_SaT1_Y313F_Rep1 / OsDEP1_SaT1_Y313F_Rep2 / OsDEP1_SaT1_Y313F_Rep3 / OsDEP1_SaT1_Y315M_Rep1 / OsDEP1_SaT1_Y315M_Rep2 / OsDEP1_SaT1_Y315M_Rep3 / OsDEP1_SaT1_YEE_Rep1 / OsDEP1_SaT1_YEE_Rep2 / OsDEP1_SaT1_YEE_Rep3 / OsDEP1_SaT1_eA3A_Rep1 / OsDEP1_SaT1_eA3A_Rep2 / OsDEP1_SaT1_eA3A_Rep3 / Zhonghua 11
	OsDEP1_SaT2	Oryza sativa Japonica Group OsDEP1_SaT2_A3A_Rep1 / OsDEP1_SaT2_A3A_Rep2 / OsDEP1_SaT2_A3A_Rep3 / OsDEP1_SaT2_A3B_Rep1 / OsDEP1_SaT2_A3B_Rep2 / OsDEP1_SaT2_A3B_Rep3 / OsDEP1_SaT2_A3Bctd_Rep1 / OsDEP1_SaT2_A3Bctd_Rep2 / OsDEP1_SaT2_A3Bctd_Rep3 / OsDEP1_SaT2_BE3_Rep1 / OsDEP1_SaT2_BE3_Rep2 / OsDEP1_SaT2_BE3_Rep3 / OsDEP1_SaT2_CK_Rep1 / OsDEP1_SaT2_CK_Rep2 / OsDEP1_SaT2_CK_Rep3 / OsDEP1_SaT2_D314H_Rep1 / OsDEP1_SaT2_D314H_Rep2 / OsDEP1_SaT2_D314H_Rep3 / OsDEP1_SaT2_D314R_Rep1 / OsDEP1_SaT2_D314R_Rep2 / OsDEP1_SaT2_D314R_Rep3 / OsDEP1_SaT2_F308K_Rep1 / OsDEP1_SaT2_F308K_Rep2 / OsDEP1_SaT2_F308K_Rep3 / OsDEP1_SaT2_KF1_Rep1 / OsDEP1_SaT2_KF1_Rep2 / OsDEP1_SaT2_KF1_Rep3 / OsDEP1_SaT2_KF2_Rep1 / OsDEP1_SaT2_KF2_Rep2 / OsDEP1_SaT2_KF2_Rep3 / OsDEP1_SaT2_KKR_Rep1 / OsDEP1_SaT2_KKR_Rep2 / OsDEP1_SaT2_KKR_Rep3 / OsDEP1_SaT2_KK_Rep1 / OsDEP1_SaT2_KK_Rep2 / OsDEP1_SaT2_KK_Rep3 / OsDEP1_SaT2_KR_Rep1 / OsDEP1_SaT2_KR_Rep2 / OsDEP1_SaT2_KR_Rep3 / OsDEP1_SaT2_KVF_Rep1 / OsDEP1_SaT2_KVF_Rep2 / OsDEP1_SaT2_KVF_Rep3 / OsDEP1_SaT2_L230K_Rep1 / OsDEP1_SaT2_L230K_Rep2 / OsDEP1_SaT2_L230K_Rep3 / OsDEP1_SaT2_N240A_Rep1 / OsDEP1_SaT2_N240A_Rep2 / OsDEP1_SaT2_N240A_Rep3 / OsDEP1_SaT2_R128A_Rep1 / OsDEP1_SaT2_R128A_Rep2 / OsDEP1_SaT2_R128A_Rep3 / OsDEP1_SaT2_R210A_Rep1 / OsDEP1_SaT2_R210A_Rep2 / OsDEP1_SaT2_R210A_Rep3 / OsDEP1_SaT2_R210K_Rep1 / OsDEP1_SaT2_R210K_Rep2 / OsDEP1_SaT2_R210K_Rep3 / OsDEP1_SaT2_R211K_Rep1 / OsDEP1_SaT2_R211K_Rep2 / OsDEP1_SaT2_R211K_Rep3 / OsDEP1_SaT2_R311K_Rep1 / OsDEP1_SaT2_R311K_Rep2 / OsDEP1_SaT2_R311K_Rep3 / OsDEP1_SaT2_RK_Rep1 / OsDEP1_SaT2_RK_Rep2 / OsDEP1_SaT2_RK_Rep3 / OsDEP1_SaT2_RM_Rep1 / OsDEP1_SaT2_RM_Rep2 / OsDEP1_SaT2_RM_Rep3 / OsDEP1_SaT2_T214C_Rep1 / OsDEP1_SaT2_T214C_Rep2 / OsDEP1_SaT2_T214C_Rep3 / OsDEP1_SaT2_T214G_Rep1 / OsDEP1_SaT2_T214G_Rep2 / OsDEP1_SaT2_T214G_Rep3 / OsDEP1_SaT2_T214S_Rep1 / OsDEP1_SaT2_T214S_Rep2 / OsDEP1_SaT2_T214S_Rep3 / OsDEP1_SaT2_T214V_Rep1 / OsDEP1_SaT2_T214V_Rep2 / OsDEP1_SaT2_T214V_Rep3 / OsDEP1_SaT2_VHM_Rep1 / OsDEP1_SaT2_VHM_Rep2 / OsDEP1_SaT2_VHM_Rep3 / OsDEP1_SaT2_VR_Rep1 / OsDEP1_SaT2_VR_Rep2 / OsDEP1_SaT2_VR_Rep3 / OsDEP1_SaT2_W281H_Rep1 / OsDEP1_SaT2_W281H_Rep2 / OsDEP1_SaT2_W281H_Rep3 / OsDEP1_SaT2_Y130F_Rep1 / OsDEP1_SaT2_Y130F_Rep2 / OsDEP1_SaT2_Y130F_Rep3 / OsDEP1_SaT2_Y313F_Rep1 / OsDEP1_SaT2_Y313F_Rep2 / OsDEP1_SaT2_Y313F_Rep3 / OsDEP1_SaT2_Y315M_Rep1 / OsDEP1_SaT2_Y315M_Rep2 / OsDEP1_SaT2_Y315M_Rep3 / OsDEP1_SaT2_YEE_Rep1 / OsDEP1_SaT2_YEE_Rep2 / OsDEP1_SaT2_YEE_Rep3 / OsDEP1_SaT2_eA3A_Rep1 / OsDEP1_SaT2_eA3A_Rep2 / OsDEP1_SaT2_eA3A_Rep3 / Zhonghua 11
	OsEPSPS_Cpf1T1	Oryza sativa Japonica Group OsEPSPS_Cpf1T1_dLbCpf1_Rep1 / OsEPSPS_Cpf1T1_dLbCpf1_Rep2 / OsEPSPS_Cpf1T1_dLbCpf1_Rep3 / OsEPSPS_Cpf1T1_ssDNA_CK_Rep1 / OsEPSPS_Cpf1T1_ssDNA_CK_Rep2 / OsEPSPS_Cpf1T1_ssDNA_CK_Rep3 / Zhonghua 11
	OsPDS_Cpf1T1	Oryza sativa Japonica Group OsPDS_Cpf1T1_dLbCpf1_Rep1 / OsPDS_Cpf1T1_dLbCpf1_Rep2 / OsPDS_Cpf1T1_dLbCpf1_Rep3 / OsPDS_Cpf1T1_ssDNA_CK_Rep1 / OsPDS_Cpf1T1_ssDNA_CK_Rep2 / OsPDS_Cpf1T1_ssDNA_CK_Rep3 / Zhonghua 11
	eA3A-BE3	Oryza sativa Japonica Group Zhonghua 11 / eA3A-BE3-#1 / eA3A-BE3-#2 / eA3A-BE3-#3 / eA3A-BE3-#4 / eA3A-BE3-#5 / eA3A-BE3-#6 / eA3A-BE3-#7 / eA3A-BE3-#8