Protein : Qrob_P0208200.2 Q. robur
Protein Identifier  ? Qrob_P0208200.2 Organism . Name  Quercus robur
Score  83.3 Score Type  egn
Protein Description  (M=7) PTHR10110:SF101 - SODIUM/HYDROGEN EXCHANGER 4 (PTHR10110:SF101) Gene Prediction Quality  validated
Protein length 

Sequence

Length: 538  
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0 Synonyms

11 GO Terms

Identifier Name Description
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0006814 sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0006812 cation transport The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0015299 solute:proton antiporter activity Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).
GO:0006885 regulation of pH Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
GO:0015385 sodium:proton antiporter activity Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
GO:0005774 vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0009651 response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
GO:0055075 potassium ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.

28 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa003943mg 1 535 + 535 Gaps:4 100.00 539 85.16 0.0 hypothetical protein
blastp_kegg lcl|pmum:103318539 1 535 + 535 Gaps:4 100.00 539 84.60 0.0 sodium/hydrogen exchanger 1
blastp_kegg lcl|mdm:103434125 4 530 + 527 Gaps:5 98.15 542 84.40 0.0 sodium/hydrogen exchanger 2-like
blastp_kegg lcl|pxb:103943799 4 529 + 526 Gaps:5 97.97 542 84.37 0.0 sodium/hydrogen exchanger 2-like
blastp_kegg lcl|fve:101303946 1 533 + 533 Gaps:8 99.63 543 82.62 0.0 sodium/hydrogen exchanger 2-like
blastp_kegg lcl|pxb:103934031 4 530 + 527 Gaps:5 98.15 542 83.83 0.0 NHX sodium/hydrogen exchanger 2-like
blastp_kegg lcl|pxb:103954467 4 530 + 527 Gaps:7 98.16 544 83.71 0.0 sodium/hydrogen exchanger 2-like
blastp_kegg lcl|mdm:103423578 4 530 + 527 Gaps:7 98.16 544 83.33 0.0 sodium/hydrogen exchanger 2-like
blastp_kegg lcl|tcc:TCM_025970 4 530 + 527 Gaps:6 97.79 543 82.67 0.0 Sodium/hydrogen exchanger
blastp_kegg lcl|csv:101224843 5 529 + 525 Gaps:2 98.68 532 82.10 0.0 sodium/hydrogen exchanger 2-like
blastp_uniprot_sprot sp|Q56XP4|NHX2_ARATH 10 530 + 521 Gaps:10 97.25 546 79.85 0.0 Sodium/hydrogen exchanger 2 OS Arabidopsis thaliana GN NHX2 PE 2 SV 2
blastp_uniprot_sprot sp|Q68KI4|NHX1_ARATH 9 530 + 522 Gaps:8 97.77 538 79.28 0.0 Sodium/hydrogen exchanger 1 OS Arabidopsis thaliana GN NHX1 PE 1 SV 2
blastp_uniprot_sprot sp|Q84WG1|NHX3_ARATH 1 498 + 498 Gaps:5 100.00 503 71.77 0.0 Sodium/hydrogen exchanger 3 OS Arabidopsis thaliana GN NHX3 PE 2 SV 2
blastp_uniprot_sprot sp|Q8S397|NHX4_ARATH 18 515 + 498 Gaps:8 95.65 529 58.30 0.0 Sodium/hydrogen exchanger 4 OS Arabidopsis thaliana GN NHX4 PE 2 SV 2
blastp_uniprot_sprot sp|Q8R4D1|SL9A8_MOUSE 26 477 + 452 Gaps:39 77.26 576 34.61 1e-62 Sodium/hydrogen exchanger 8 OS Mus musculus GN Slc9a8 PE 2 SV 1
blastp_uniprot_sprot sp|Q4L208|SL9A8_RAT 26 477 + 452 Gaps:39 77.39 575 34.61 1e-62 Sodium/hydrogen exchanger 8 OS Rattus norvegicus GN Slc9a8 PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZJ75|SL9A8_CHICK 26 516 + 491 Gaps:46 84.15 574 32.92 6e-62 Sodium/hydrogen exchanger 8 OS Gallus gallus PE 2 SV 1
blastp_uniprot_sprot sp|Q9Y2E8|SL9A8_HUMAN 26 516 + 491 Gaps:54 83.13 581 33.13 2e-60 Sodium/hydrogen exchanger 8 OS Homo sapiens GN SLC9A8 PE 1 SV 4
blastp_uniprot_sprot sp|Q552S0|NHE1_DICDI 48 464 + 417 Gaps:29 58.75 674 36.11 4e-55 Sodium/hydrogen exchanger 1 OS Dictyostelium discoideum GN nhe1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8BZ00|SL9A9_MOUSE 78 517 + 440 Gaps:58 64.91 644 33.73 2e-51 Sodium/hydrogen exchanger 9 OS Mus musculus GN Slc9a9 PE 2 SV 1
rpsblast_cdd gnl|CDD|162063 47 510 + 464 Gaps:54 78.00 559 32.57 1e-59 TIGR00840 b_cpa1 sodium/hydrogen exchanger 3. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36)The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria blue green bacteria yeast plants and animals.Transporters from eukaryotes have been functionally characterized and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in(1) cytoplasmic pH regulation extruding the H+ generated during metabolism and (2) salt tolerance (in plants) due to Na+ uptake into vacuoles.This Hmm is specific for the eukaryotic members members of this family.
rpsblast_cdd gnl|CDD|30375 52 449 + 398 Gaps:23 88.81 429 22.83 1e-32 COG0025 NhaP NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].
rpsblast_cdd gnl|CDD|201544 83 439 + 357 Gaps:38 87.30 370 29.41 3e-29 pfam00999 Na_H_Exchanger Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
rpsblast_cdd gnl|CDD|129911 80 443 + 364 Gaps:32 68.57 525 23.61 3e-21 TIGR00831 a_cpa1 Na+/H+ antiporter bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria blue green bacteria yeast plants and animals. Transporters from eukaryotes have been functionally characterized and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation extruding the H+ generated during metabolism and (2) salt tolerance (in plants) due to Na+ uptake into vacuoles. This Hmm is specific for the bacterial members of this family.
rpsblast_cdd gnl|CDD|33074 93 445 + 353 Gaps:49 55.40 574 26.10 3e-12 COG3263 COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism].
rpsblast_cdd gnl|CDD|180017 119 447 + 329 Gaps:58 52.14 562 27.99 1e-08 PRK05326 PRK05326 potassium/proton antiporter Reviewed.
rpsblast_kog gnl|CDD|37176 3 530 + 528 Gaps:42 95.65 575 44.73 1e-145 KOG1965 KOG1965 KOG1965 Sodium/hydrogen exchanger protein [Inorganic ion transport and metabolism].
rpsblast_kog gnl|CDD|37177 46 512 + 467 Gaps:57 65.37 670 31.74 6e-54 KOG1966 KOG1966 KOG1966 Sodium/hydrogen exchanger protein [Inorganic ion transport and metabolism].

35 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 113 137 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 218 240 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 169 174 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 73 83 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 417 437 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 102 112 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 252 268 17 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PRINTS 113 121 9 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
PRINTS 98 112 15 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
PRINTS 153 163 11 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
PRINTS 84 95 12 PR01084 "Reactome:REACT_15518" Na+/H+ exchanger signature IPR004709
Phobius 199 217 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 343 363 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 274 292 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 293 303 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 324 342 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 241 251 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 32 443 412 PF00999 none Sodium/hydrogen exchanger family IPR006153
PANTHER 1 516 516 PTHR10110 "Reactome:REACT_15518";signature_desc=SODIUM/HYDROGEN EXCHANGER none IPR018422
PANTHER 1 516 516 PTHR10110:SF101 none none IPR029872
TIGRFAM 25 452 428 TIGR00840 "Reactome:REACT_15518" b_cpa1: sodium/hydrogen exchanger 3 IPR004709
Phobius 44 54 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 269 273 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 175 198 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 384 405 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 364 383 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 438 537 100 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 20 43 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 406 416 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 149 168 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

11 Localization

Analysis Start End Length
TMHMM 111 133 22
TMHMM 146 168 22
TMHMM 267 289 22
TMHMM 347 369 22
TMHMM 304 326 22
TMHMM 218 240 22
TMHMM 416 438 22
TMHMM 384 403 19
TMHMM 53 72 19
TMHMM 84 101 17
TMHMM 21 43 22

7 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 40   Secretory pathway 4 0.694 0.045 NON-PLANT 40