Protein : Qrob_P0207000.2 Q. robur
Protein Identifier  ? Qrob_P0207000.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) 1.14.99.7 - Transferred entry: 1.14.13.132. Code Enzyme  EC:1.14.99.7
Gene Prediction Quality  validated Protein length 

Sequence

Length: 532  
Kegg Orthology  K00511
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0050660 flavin adenine dinucleotide binding Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0004506 squalene monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_034641 7 528 + 522 Gaps:5 99.62 523 87.91 0.0 Squalene monooxygenase isoform 1
blastp_kegg lcl|cmo:103493632 6 527 + 522 Gaps:3 99.05 524 84.97 0.0 squalene monooxygenase-like
blastp_kegg lcl|csv:101204949 6 527 + 522 Gaps:3 99.05 524 84.59 0.0 squalene monooxygenase-like
blastp_kegg lcl|rcu:RCOM_1585750 7 528 + 522 Gaps:8 99.25 534 82.45 0.0 Squalene monooxygenase putative (EC:1.14.99.7)
blastp_kegg lcl|gmx:100795522 7 527 + 521 Gaps:7 99.24 526 84.29 0.0 squalene monooxygenase-like
blastp_kegg lcl|csv:101213038 6 527 + 522 Gaps:4 99.24 528 82.82 0.0 squalene monooxygenase-like
blastp_kegg lcl|fve:101297207 4 525 + 522 Gaps:9 96.67 541 83.75 0.0 squalene monooxygenase-like
blastp_kegg lcl|cam:101491995 9 526 + 518 Gaps:4 98.66 523 83.72 0.0 squalene monooxygenase-like
blastp_kegg lcl|cmo:103487810 6 527 + 522 Gaps:4 99.24 528 82.63 0.0 squalene monooxygenase-like
blastp_kegg lcl|vvi:100265235 8 526 + 519 Gaps:3 99.24 524 81.73 0.0 squalene monooxygenase-like
blastp_pdb 2x3n_A 65 368 + 304 Gaps:54 76.19 399 26.97 3e-08 mol:protein length:399 PROBABLE FAD-DEPENDENT MONOOXYGENASE
blastp_uniprot_sprot sp|O48651|ERG1_PANGI 3 527 + 525 Gaps:9 96.10 539 79.15 0.0 Squalene monooxygenase OS Panax ginseng PE 2 SV 1
blastp_uniprot_sprot sp|Q9SM02|ERG14_ARATH 23 530 + 508 Gaps:2 95.29 531 78.66 0.0 Squalene epoxidase 1 OS Arabidopsis thaliana GN SQE1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8VYH2|ERG16_ARATH 13 524 + 512 Gaps:11 95.43 525 76.85 0.0 Squalene epoxidase 3 OS Arabidopsis thaliana GN SQE3 PE 1 SV 1
blastp_uniprot_sprot sp|O81000|ERG15_ARATH 4 526 + 523 Gaps:9 87.86 585 75.10 0.0 Squalene epoxidase 2 mitochondrial OS Arabidopsis thaliana GN SQE2 PE 1 SV 1
blastp_uniprot_sprot sp|O65404|ERG11_ARATH 65 524 + 460 Gaps:3 89.73 516 52.48 3e-175 Squalene epoxidase 5 OS Arabidopsis thaliana GN SQE5 PE 2 SV 2
blastp_uniprot_sprot sp|O65402|ERG12_ARATH 19 524 + 506 Gaps:17 96.13 517 50.30 2e-171 Squalene epoxidase 6 OS Arabidopsis thaliana GN SQE6 PE 2 SV 1
blastp_uniprot_sprot sp|O65726|ERG12_BRANA 65 524 + 460 Gaps:2 89.19 518 49.78 4e-168 Squalene monooxygenase 1 2 OS Brassica napus GN SQP1 2 PE 2 SV 1
blastp_uniprot_sprot sp|O65727|ERG11_BRANA 63 524 + 462 Gaps:13 89.53 506 52.54 3e-166 Squalene monooxygenase 1 1 OS Brassica napus GN SQP1 1 PE 2 SV 1
blastp_uniprot_sprot sp|O65403|ERG13_ARATH 19 523 + 505 Gaps:18 96.32 516 47.08 3e-157 Squalene epoxidase 4 OS Arabidopsis thaliana GN SQE4 PE 2 SV 1
blastp_uniprot_sprot sp|Q14534|ERG1_HUMAN 32 507 + 476 Gaps:25 83.45 574 45.93 4e-123 Squalene monooxygenase OS Homo sapiens GN SQLE PE 1 SV 3
rpsblast_cdd gnl|CDD|178566 19 524 + 506 Gaps:16 96.50 514 50.60 1e-159 PLN02985 PLN02985 squalene monooxygenase.
rpsblast_cdd gnl|CDD|192047 214 487 + 274 Gaps:4 100.00 276 60.51 1e-133 pfam08491 SE Squalene epoxidase. This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.
rpsblast_cdd gnl|CDD|185578 63 510 + 448 Gaps:78 87.83 567 38.96 1e-120 PTZ00367 PTZ00367 squalene epoxidase Provisional.
rpsblast_cdd gnl|CDD|30999 65 441 + 377 Gaps:14 95.35 387 22.76 6e-36 COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].
rpsblast_cdd gnl|CDD|30989 63 418 + 356 Gaps:40 88.89 396 22.73 4e-17 COG0644 FixC Dehydrogenases (flavoproteins) [Energy production and conversion].
rpsblast_cdd gnl|CDD|136171 65 414 + 350 Gaps:40 89.69 388 28.74 6e-16 PRK07045 PRK07045 putative monooxygenase Reviewed.
rpsblast_cdd gnl|CDD|180451 63 231 + 169 Gaps:44 41.52 407 31.95 7e-13 PRK06185 PRK06185 hypothetical protein Provisional.
rpsblast_cdd gnl|CDD|200151 65 367 + 303 Gaps:49 96.27 295 22.18 3e-11 TIGR02032 GG-red-SF geranylgeranyl reductase family. This HMM represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates.
rpsblast_kog gnl|CDD|36512 53 526 + 474 Gaps:1 93.32 509 71.37 0.0 KOG1298 KOG1298 KOG1298 Squalene monooxygenase [Lipid transport and metabolism].

20 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 436 455 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 479 484 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 215 487 273 PF08491 "KEGG:00100+1.14.13.132","KEGG:00909+1.14.13.132","MetaCyc:PWY-5670","MetaCyc:PWY-6098","UniPathway:UPA00767" Squalene epoxidase IPR013698
PRINTS 214 229 16 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 357 373 17 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 65 87 23 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
PRINTS 342 357 16 PR00420 none Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature none
SUPERFAMILY 64 235 172 SSF51905 none none none
SUPERFAMILY 329 439 111 SSF51905 none none none
PANTHER 30 527 498 PTHR10835 none none none
Phobius 505 531 27 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Pfam 68 94 27 PF13450 none NAD(P)-binding Rossmann-like domain none
Phobius 32 435 404 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 456 460 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 461 478 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 62 238 177 G3DSA:3.50.50.60 none none none
Gene3D 340 375 36 G3DSA:3.50.50.60 none none none
Phobius 12 31 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 485 504 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 11 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none

1 Localization

Analysis Start End Length
TMHMM 9 31 22

9 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2004_QTL4_peak_Bud_burst_A4 Qrob_Chr09 9 s_1BY6BQ_440 s_1AOIKO_756 16,45 0 27,45 lod 4,5 10,6
Bourran_2000_2002_QTL7_Delta.F Qrob_Chr09 9 v_5944_442 s_1BA1PC_866 23.51 10,96 35,74 lod 4.1466 0.041
Bourran2_2003_QTL11_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 4,16 48,16 lod 2,3 5,1
Bourran2_2003_QTL13_peak_Bud_burst_A4 Qrob_Chr09 9 s_1AP8MN_635 s_1A3QQ_692 18,18 10,88 25,88 lod 3,4 7,2
Bourran2_2004_QTL12_peak_Bud_burst_3P Qrob_Chr09 9 s_1BDO6G_250 s_1A83AM_496 34,31 9,31 44,31 lod 3,6 7,6
Bourran2_2004_QTL14_peak_Bud_burst_A4 Qrob_Chr09 9 s_1BY6BQ_440 s_1AOIKO_756 16,83 10,33 22,33 lod 3,8 9
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nSecLBD_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 35,81 34,88 37,45 lod 4.4 10.4
PM_1999_QTL15_peak_Bud_burst_3P Qrob_Chr09 9 s_1CGP2H_273 v_15801_330 27,16 9,16 47,16 lod 3,6 6,5

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 31   Secretory pathway 1 0.980 0.018 NON-PLANT 31