Protein : Qrob_P0077810.2 Q. robur
Protein Identifier  ? Qrob_P0077810.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=1) 3.4.22.15 - Cathepsin L. Code Enzyme  EC:3.4.22.15
Gene Prediction Quality  validated Protein length 

Sequence

Length: 384  
Kegg Orthology  K01373
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10031865mg 4 383 + 380 Gaps:18 98.66 373 72.28 0.0 hypothetical protein
blastp_kegg lcl|cit:102609994 4 383 + 380 Gaps:18 98.66 373 72.28 0.0 cysteine proteinase 1-like
blastp_kegg lcl|pper:PRUPE_ppa007240mg 6 381 + 376 Gaps:24 97.08 377 72.40 0.0 hypothetical protein
blastp_kegg lcl|vvi:100244387 5 383 + 379 Gaps:19 99.73 375 73.80 0.0 cysteine proteinase 15A-like
blastp_kegg lcl|mdm:103426367 6 380 + 375 Gaps:20 97.04 372 72.85 0.0 cysteine proteinase 15A
blastp_kegg lcl|tcc:TCM_043315 4 381 + 378 Gaps:28 98.43 382 72.07 0.0 Papain family cysteine protease
blastp_kegg lcl|pmum:103332313 6 381 + 376 Gaps:24 97.08 377 71.04 0.0 cysteine proteinase 15A
blastp_kegg lcl|rcu:RCOM_0253350 38 383 + 346 Gaps:15 86.88 381 77.04 0.0 cysteine protease putative (EC:3.4.22.41)
blastp_kegg lcl|fve:101307832 9 380 + 372 Gaps:20 95.74 376 72.50 0.0 cysteine proteinase 15A-like
blastp_kegg lcl|cam:101500737 4 379 + 376 Gaps:17 94.83 387 68.39 0.0 cysteine proteinase 15A-like
blastp_pdb 2p86_A 143 379 + 237 Gaps:35 98.60 215 48.58 7e-55 mol:protein length:215 Cysteine protease
blastp_pdb 2p7u_A 143 379 + 237 Gaps:35 98.60 215 48.58 7e-55 mol:protein length:215 Cysteine protease
blastp_pdb 1m6d_B 143 379 + 237 Gaps:30 98.60 214 51.66 1e-54 mol:protein length:214 Cathepsin F
blastp_pdb 1m6d_A 143 379 + 237 Gaps:30 98.60 214 51.66 1e-54 mol:protein length:214 Cathepsin F
blastp_pdb 2o6x_A 64 376 + 313 Gaps:44 93.87 310 41.92 2e-53 mol:protein length:310 Secreted cathepsin L 1
blastp_pdb 3lxs_C 143 379 + 237 Gaps:35 98.60 215 48.58 4e-52 mol:protein length:215 Cruzain
blastp_pdb 3lxs_A 143 379 + 237 Gaps:35 98.60 215 48.58 4e-52 mol:protein length:215 Cruzain
blastp_pdb 3kku_A 143 379 + 237 Gaps:35 98.60 215 48.58 4e-52 mol:protein length:215 Cruzipain
blastp_pdb 3i06_A 143 379 + 237 Gaps:35 98.60 215 48.58 4e-52 mol:protein length:215 Cruzipain
blastp_pdb 2oz2_C 143 379 + 237 Gaps:35 98.60 215 48.58 4e-52 mol:protein length:215 Cruzipain
blastp_uniprot_sprot sp|P25804|CYSP_PEA 24 383 + 360 Gaps:19 95.59 363 52.74 5e-128 Cysteine proteinase 15A OS Pisum sativum PE 1 SV 1
blastp_uniprot_sprot sp|P43296|RD19A_ARATH 50 383 + 334 Gaps:15 87.23 368 55.14 3e-122 Cysteine proteinase RD19a OS Arabidopsis thaliana GN RD19A PE 2 SV 1
blastp_uniprot_sprot sp|Q10716|CYSP1_MAIZE 47 378 + 332 Gaps:25 88.14 371 52.91 1e-120 Cysteine proteinase 1 OS Zea mays GN CCP1 PE 2 SV 1
blastp_uniprot_sprot sp|P43295|A494_ARATH 50 383 + 334 Gaps:15 88.92 361 52.96 2e-120 Probable cysteine proteinase A494 OS Arabidopsis thaliana GN At2g21430 PE 2 SV 2
blastp_uniprot_sprot sp|P04988|CYSP1_DICDI 54 379 + 326 Gaps:39 92.42 343 46.37 5e-84 Cysteine proteinase 1 OS Dictyostelium discoideum GN cprA PE 1 SV 2
blastp_uniprot_sprot sp|Q26534|CATL_SCHMA 54 379 + 326 Gaps:35 94.36 319 45.85 6e-78 Cathepsin L OS Schistosoma mansoni GN CL1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9R013|CATF_MOUSE 42 379 + 338 Gaps:44 67.53 462 48.72 4e-73 Cathepsin F OS Mus musculus GN Ctsf PE 2 SV 1
blastp_uniprot_sprot sp|Q9VN93|CPR1_DROME 57 379 + 323 Gaps:36 49.67 614 45.25 1e-72 Putative cysteine proteinase CG12163 OS Drosophila melanogaster GN CG12163 PE 2 SV 2
blastp_uniprot_sprot sp|Q9UBX1|CATF_HUMAN 5 379 + 375 Gaps:53 73.97 484 44.41 6e-72 Cathepsin F OS Homo sapiens GN CTSF PE 1 SV 1
blastp_uniprot_sprot sp|P25779|CYSP_TRYCR 55 379 + 325 Gaps:41 64.24 467 44.67 1e-68 Cruzipain OS Trypanosoma cruzi PE 1 SV 1

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 52 379 328 G3DSA:3.90.70.10 none none none
PANTHER 57 378 322 PTHR12411 none none IPR013128
Phobius 22 26 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Pfam 142 378 237 PF00112 none Papain family cysteine protease IPR000668
ProSitePatterns 343 362 20 PS00640 none Eukaryotic thiol (cysteine) proteases asparagine active site. IPR025661
ProSitePatterns 160 171 12 PS00139 none Eukaryotic thiol (cysteine) proteases cysteine active site. IPR000169
SUPERFAMILY 54 378 325 SSF54001 none none none
Phobius 8 21 14 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Phobius 27 383 357 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 57 378 322 PTHR12411:SF296 none none none
ProSitePatterns 319 329 11 PS00639 none Eukaryotic thiol (cysteine) proteases histidine active site. IPR025660
Phobius 1 7 7 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Pfam 57 113 57 PF08246 none Cathepsin propeptide inhibitor domain (I29) IPR013201
SMART 142 379 238 SM00645 none Papain family cysteine protease IPR000668
Phobius 1 26 26 SIGNAL_PEPTIDE none Signal peptide region none
SMART 57 113 57 SM00848 none Cathepsin propeptide inhibitor domain (I29) IPR013201
PRINTS 321 331 11 PR00705 none Papain cysteine protease (C1) family signature IPR000668
PRINTS 343 349 7 PR00705 none Papain cysteine protease (C1) family signature IPR000668
PRINTS 160 175 16 PR00705 none Papain cysteine protease (C1) family signature IPR000668

3 Localization

Analysis Start End Length
SignalP_GRAM_POSITIVE 1 27 26
SignalP_GRAM_NEGATIVE 1 26 25
SignalP_EUK 1 27 26

8 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL3_d13Cf Qrob_Chr08 8 v_5216_549 v_11625_20 37.08 12,26 54,9 lod 6.5888 0.04

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 26   Secretory pathway 1 0.964 0.020 NON-PLANT 26