Protein : Qrob_P0032990.2 Q. robur
Protein Identifier  ? Qrob_P0032990.2 Organism . Name  Quercus robur
Score  96.1 Score Type  egn
Protein Description  (M=1) K05285 - phosphatidylinositol glycan, class N [EC:2.7.-.-] Gene Prediction Quality  validated
Protein length 

Sequence

Length: 936  
Kegg Orthology  K05285
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0005789 endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
GO:0006506 GPI anchor biosynthetic process The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
GO:0008484 sulfuric ester hydrolase activity Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2.

26 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_016816 3 935 + 933 Gaps:58 99.90 986 74.31 0.0 GPI ethanolamine phosphate transferase putative isoform 1
blastp_kegg lcl|vvi:100254323 1 935 + 935 Gaps:59 100.00 986 74.75 0.0 GPI ethanolamine phosphate transferase 1-like
blastp_kegg lcl|cic:CICLE_v10010988mg 3 935 + 933 Gaps:64 99.90 982 73.39 0.0 hypothetical protein
blastp_kegg lcl|cit:102631173 3 935 + 933 Gaps:64 99.90 982 72.99 0.0 GPI ethanolamine phosphate transferase 1-like
blastp_kegg lcl|pmum:103329911 16 935 + 920 Gaps:57 98.88 984 73.07 0.0 GPI ethanolamine phosphate transferase 1-like
blastp_kegg lcl|rcu:RCOM_0852450 1 934 + 934 Gaps:64 99.90 981 72.24 0.0 GPI ethanolamine phosphate transferase putative
blastp_kegg lcl|mdm:103442287 9 935 + 927 Gaps:60 99.69 980 73.90 0.0 GPI ethanolamine phosphate transferase 1
blastp_kegg lcl|gmx:100800363 4 934 + 931 Gaps:69 99.69 977 73.92 0.0 GPI ethanolamine phosphate transferase 1-like
blastp_kegg lcl|pxb:103928446 9 935 + 927 Gaps:60 99.69 980 73.59 0.0 GPI ethanolamine phosphate transferase 1
blastp_kegg lcl|pxb:103939638 29 935 + 907 Gaps:60 97.65 980 74.19 0.0 GPI ethanolamine phosphate transferase 1-like
blastp_uniprot_sprot sp|Q2U0S9|MCD4_ASPOR 40 923 + 884 Gaps:133 94.03 1022 38.40 0.0 GPI ethanolamine phosphate transferase 1 OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN mcd4 PE 3 SV 1
blastp_uniprot_sprot sp|Q4W9R7|MCD4_ASPFU 40 923 + 884 Gaps:135 93.51 1032 38.34 0.0 GPI ethanolamine phosphate transferase 1 OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN mcd4 PE 2 SV 1
blastp_uniprot_sprot sp|Q7SAP1|MCD4_NEUCR 40 934 + 895 Gaps:108 96.08 996 37.41 6e-180 GPI ethanolamine phosphate transferase 1 OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN mcd-4 PE 3 SV 1
blastp_uniprot_sprot sp|Q9R1S3|PIGN_MOUSE 40 923 + 884 Gaps:109 98.28 931 39.02 7e-180 GPI ethanolamine phosphate transferase 1 OS Mus musculus GN Pign PE 2 SV 2
blastp_uniprot_sprot sp|Q4ILH3|MCD4_GIBZE 40 925 + 886 Gaps:125 96.33 981 38.41 1e-178 GPI ethanolamine phosphate transferase 1 OS Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) GN MCD4 PE 3 SV 1
blastp_uniprot_sprot sp|O95427|PIGN_HUMAN 40 919 + 880 Gaps:128 97.74 931 38.90 2e-178 GPI ethanolamine phosphate transferase 1 OS Homo sapiens GN PIGN PE 1 SV 1
blastp_uniprot_sprot sp|Q757X5|MCD4_ASHGO 29 925 + 897 Gaps:134 98.49 925 39.41 3e-173 GPI ethanolamine phosphate transferase 1 OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN MCD4 PE 3 SV 2
blastp_uniprot_sprot sp|Q6C0Z3|MCD4_YARLI 37 935 + 899 Gaps:125 99.14 932 37.55 6e-172 GPI ethanolamine phosphate transferase 1 OS Yarrowia lipolytica (strain CLIB 122 / E 150) GN MCD4 PE 3 SV 1
blastp_uniprot_sprot sp|Q6CW36|MCD4_KLULA 32 934 + 903 Gaps:140 99.56 919 38.80 6e-170 GPI ethanolamine phosphate transferase 1 OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) GN MCD4 PE 3 SV 1
blastp_uniprot_sprot sp|P36051|MCD4_YEAST 29 932 + 904 Gaps:122 99.89 919 38.34 7e-169 GPI ethanolamine phosphate transferase 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN MCD4 PE 1 SV 1
rpsblast_cdd gnl|CDD|203141 442 887 + 446 Gaps:41 100.00 441 35.15 9e-98 pfam04987 PigN Phosphatidylinositolglycan class N (PIG-N). Phosphatidylinositolglycan class N (PIG-N) is a mammalian homologue of the yeast protein MCD4P and is expressed in the endoplasmic reticulum. PIG-N is essential for glycosylphosphatidylinositol anchor synthesis. Glycosylphosphatidylinositol (GPI)-anchored proteins are cell surface-localised proteins that serve many important cellular functions.
rpsblast_cdd gnl|CDD|31713 39 309 + 271 Gaps:31 65.33 450 23.47 1e-20 COG1524 COG1524 Uncharacterized proteins of the AP superfamily [General function prediction only].
rpsblast_cdd gnl|CDD|201911 79 296 + 218 Gaps:48 66.67 342 19.30 1e-08 pfam01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin tumour cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.
rpsblast_kog gnl|CDD|37335 35 922 + 888 Gaps:116 98.98 883 44.85 0.0 KOG2124 KOG2124 KOG2124 Glycosylphosphatidylinositol anchor synthesis protein [Signal transduction mechanisms].
rpsblast_kog gnl|CDD|37336 36 396 + 361 Gaps:63 41.58 760 28.80 8e-14 KOG2125 KOG2125 KOG2125 Glycosylphosphatidylinositol anchor synthesis protein [Signal transduction mechanisms].
rpsblast_kog gnl|CDD|37337 67 898 + 832 Gaps:132 90.06 895 15.26 5e-10 KOG2126 KOG2126 KOG2126 Glycosylphosphatidylinositol anchor synthesis protein [Signal transduction mechanisms].

36 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 605 612 8 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 804 828 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 587 604 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 729 747 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 477 496 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 883 893 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 582 586 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 36 57 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 35 35 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 834 858 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 748 772 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 77 324 248 G3DSA:3.40.720.10 none none IPR017849
Gene3D 361 384 24 G3DSA:3.40.720.10 none none IPR017849
Phobius 518 522 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 452 476 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 76 324 249 SSF53649 none none IPR017850
SUPERFAMILY 361 386 26 SSF53649 none none IPR017850
Phobius 58 451 394 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Pfam 442 862 421 PF04987 "UniPathway:UPA00196" Phosphatidylinositolglycan class N (PIG-N) IPR017852
Phobius 560 581 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 541 559 19 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 635 639 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 28 922 895 PTHR12250 "UniPathway:UPA00196";signature_desc=PHOSPHATIDYLINOSITOL GLYCAN, CLASS N none IPR007070
Phobius 773 803 31 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 613 634 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 894 914 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 497 517 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 865 882 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 659 703 45 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 228 330 103 PF00884 none Sulfatase IPR000917

14 Localization

Analysis Start End Length
TMHMM 704 726 22
TMHMM 453 475 22
TMHMM 741 763 22
TMHMM 836 858 22
TMHMM 804 826 22
TMHMM 496 518 22
TMHMM 897 919 22
TMHMM 35 57 22
TMHMM 560 582 22
TMHMM 640 658 18
TMHMM 523 540 17
TMHMM 587 604 17
TMHMM 611 630 19
TMHMM 865 882 17

11 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting