2011
UMR INRA-CNRS 6175, Physiologie de la Reproduction et des Comportements (PRC)
Centre INRA de Nouzilly 37380 Nouzilly Cedex - France
Data integration is a key challenge of modern bioinformatics. It aims at providing biologists an intuitive way to explore data produced by different people in various projects. Indeed, large scale international projects generate lots of heterogeneous and unrelated data. The challenge becomes then to integrate and to link them with other publicly available data. Recent improvements in the throughput of nucleotide sequencing machines with the many applications in genomics and genetics fields critically emphasis on the necessity to have powerful information systems able to store, manipulate and explore these data.
The URGI develops a such information system called GnpIS to bridge genetic and genomic data, allowing researchers to cross genetic information (i.e Genetic maps, QTL, markers, SNPs, germplasms, genotypes, phenotypes) with genomic data (i.e. physical maps, genome annotation, expression data) for species of agronomical interest. This system is in used in the frame of many large INRA and international projects. Some perspectives on its evolution for whole genome association studies and genomic selection will be given.
Other tools developed at URGI allow efficient sequence annotation and data integration. They will be presented with as an illustration, some results obtained on transposable elements (TEs), a key feature of eukaryote genomes.
Creation date: 24 Nov 2011
eZ PublishPublication supervisor: A-F. Adam-Blondon
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